Antibacterial activity of Myrtus communis L. and Melaleuca leucadendron var. cajaputi essential oils against antibiotic-resistant bacterial strains

Background: Antimicrobial resistance (AMR) is a global threat to public health. There dire need for new antibiotics as AMR threatens our last-resort efficacy.1,2 Myrtle plants have been used in folk medicine centuries. Essential oils from these demonstrated therapeutics effects. This study aims examine the antibacterial activity of essential extracted Myrtus communis L and Melaleuca leucadendron against clinically relevant bacterial pathogens.3Methods: Bacterial growth curves bactericidal assays were performed on antibiotic-sensitive Staphylococcus aureus (SA) antibiotic low high resistant Methicillin-resistant (MRSA) strains; sensitive Klebsiella pneumoniae strains (KPS KPR). Minimum concentration (MBC) was 4 colistin E. coli strains. Results: dose-dependent all tested inhibited even after 24 hours. The dilutions ranged 6.15 μl/ml up 50 both SA, MRSA (Figure 1), Klebsiella. Further, incubation colistin-resistant with oil one hour viability bacteria by spotting agar plates further overnight. data suggest that can effectively kill pathogens. Conclusion: L. var. cajaputi possess potent potential utilizing topical treatment wound infections.